Biology at Hiram

Brad Goodner, Ph.D.

Associate Professor of Biology

Edward J. Smerek Chair of Mathematics, the Sciences, & Technology

Director, Center for Deciphering Life's Languages

HHMI Program Director

222 Colton Hall
330.569.5260
goodnerbw@hiram.edu

Education

Texas A&M University (Biochemistry), B.S.

Purdue University (Biology), Ph.D.

University of North Carolina (Plant Development), Post-doctoral education

Courses Taught

Genetics

Molecular & cellular biology

Microbiology

Advanced molecular & cellular biology

Immunology

Bioinformatics

Zoology

Research Interests

  • Functional genomics to better understand the biology of Agrobacterium tumefaciens
  • Reconstructing the evolution of chromosome II in Agrobacterium biovar 1 and 3 strains
  • Physical mapping, gap closure, & annotation for Agrobacterium biovar 2 and 3 genomes
  • Genetic/physical map, gap closure, & annotation for two Xenorhabdus genomes
  • Annotation of the Chromohalobacter salexigens (Halomonas elongata) genome
  • Finishing & annotating the Azotobacter vinelandii genome
  • Finishing & annotating the Sphingomonas elodea genome

Publications

Notes: *denotes undergraduate student, **denotes high school student

  • Latreille, P., S. Norton, S. Slater, N. Miller, B. Barbazuk, H. Bode, C. Darby, S. Forst, S. Gaudriault, B. Goodner, H. Goodrich-Blair, & B. Goldman, 2007. Optical mapping as a routine tool in bacteria genome sequencing. Genome Research (manuscript submitted).
  • Forst, S., & B. Goodner, 2006. Comparative bacterial genomics and its use in undergraduate education. Biological Control 38:47-53.
  • Slater, S.C., B.W. Goodner, J.C. Setubal, T. Burr, S. Farrand, B. Goldman, D.W. Wood, & E.W. Nester, 2006. The Agrobacterium tumefaciens C58 genome: general features and scientific impact since publication of the sequence. (invited book chapter in press).
  • Goodner, B., & C. Wheeler, 2006. Functional genomics: using reverse genetics to test bioinformatics predictions. ASM Microbe Library (peer-reviewed Web site for microbiology teaching resources).
  • Huang, W.M., J. Davis, Q. Ruan, J. Aron, B. Goodner, N. Pride*, E. Henry*, A. Sabo*, E. Telepak*, L. Joss, & S. Casjens, 2006. Linear chromosome end generating system of Agrobacterium tumefaciens C58. Journal of Biological Chemistry (manuscript submitted).
  • Goodner, B., 2006. So you want to include bioinformatics in your course – go for it! Focus on Microbiology Education 12(3):4-5.
  • Csonka, L.N., K. O’Connor, F. Larimer, P. Richardson, A. Lapidus, A.D. Ewing*, B.W. Goodner, & A. Oren, 2005. What we can deduce about metabolism in the moderate halophile Chromohalobacter salexigens from its genomic sequence. Chapter 18 in Adaptation To Life At High Salt Concentrations In Archaea, Bacteria, and Eukarya. Gunde-Cimerman, N., A. Oren, & A. Plemenita, eds. Springer-Dordrecht.
  • Goodner, B., & D. Wood, 2004. “Going after the whole genome from two different angles”, pp. 292-309 in Agrobacterium tumefaciens: From Plant Pathology to Biotechnology. Nester, E., M.P. Gordon, & A. Kerr, eds. St. Paul, MN: APS Press.
  • Goodner, B., & C. Wheeler, 2004. Genetic and physical mapping of a bacterial genome. ASM Microbe Library (peer-reviewed Web site for microbiology teaching resources).
  • Fowler, J.E., Z. Vejlupkova, B.W. Goodner, G. Lu, & R.S. Quatrano, 2004. Localization to the rhizoid tip implicates a Fucus distichus Rho family GTPase in a conserved cell polarity pathway. Planta 219:856-66.
  • Goodner, B., 2004. Genomics and undergraduate education do mix. K-BRIN Newsletter 2:6-8.
  • Goodner, B.W., C.A. Wheeler, P.J. Hall, & S.C. Slater, 2003. Massively parallel undergraduates for bacterial genome finishing. ASM News 69:584-585.
  • Goodner, B., G. Hinkle, S. Gattung, N. Miller, M. Blanchard, B. Qurollo, B.S. Goldman, Y. Cao, M. Askenazi, C. Halling, L. Mullin, K. Houmiel, J. Gordon, M. Vaudin, O. Iartchouk, A. Epp, F. Liu, C. Wollam, M. Allinger, D. Doughty*, C. Scott*, C. Lappas*, B. Markelz*, C. Flanagan*, C. Crowell*, J. Gurson*, C. Lomo*, C. Sear*, G. Strub*, C. Cielo*, & S. Slater, 2001. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. Science 294:2323-2328.
  • Goodner, B.W., B.P. Markelz*, M.C. Flanagan*, C.B. Crowell, Jr.*, J.L. Racette*, B.A. Schilling*, L.M. Halfon*, J.S. Mellors*, & G. Grabowski*, 1999. Combined genetic and physical map of the complex genome of Agrobacteriu tumefaciens. Journal of Bacteriology 181:5160-5166.
  • Goodner, B.W., L.E. Jacobson**, & A.L. Goodner, 1998. The role of egg size and composition in artificial nest predation experiments. Virginia Journal of Science 49:221-225.
  • Rabenold, K.N., P.T. Fauth, B.W. Goodner, J.A. Sadowski, & P.G. Parker, 1998. Response of avian communities to disturbance by an exotic insect in spruce-fir forests of the southern Appalachians. Conservation Biology 12:177-189.
  • Goodner, B., J.D. Davis, & R.S. Quatrano, 1995. Sequence of actin cDNA from Fucus disticus. Plant Physiology 107:1007-1008.
  • Goodner, B., & R.S. Quatrano, 1993. Fucus embryogenesis: A model to study the establishment of polarity. The Plant Cell 5:1471-1481.
  • Csonka, L.N., S.B. Gelvin, B.W. Goodner, C.S. Orser, D. Siemieniak, & J.L. Slightom, 1988. Nucleotide sequence of a mutation in the proB gene of Escherichia coli that confers proline overproduction and enhanced tolerance to osmotic stress. Gene 64:199-205.
  • Orser, C.S., B.W. Goodner, M. Johnston, S.B. Gelvin, & L.N. Csonka, 1988. The Escherichia coli proB gene corrects the proline auxotrophy of Saccharomyces cerevisiae pro1 mutants. Molecular & General Genetics 212:124-128.
 

Important Links on Hiram's website